عنوان

Numerical modeling of COVID-19 neurological effects

شابک

9781003243052

شابک

9781032152110

شماره

E3295

زبان متن نوشتاري يا گفتاري و مانند آن

انگلیسی

عنوان اصلي

Numerical modeling of COVID-19 neurological effects

نام عام مواد

[Electronic book]

ساير اطلاعات عنواني

: ODE/PDE analysis in R

نام نخستين پديدآور

/ William Schiesser.

محل نشرو پخش و غیره

Boca Raton

نام ناشر، پخش کننده و غيره

: CRC Press

تاریخ نشرو بخش و غیره

, 2021.

نام خاص و کميت اثر

1 v.

ساير جزييات

; ill.

متن يادداشت

William E. Schiesser is Emeritus McCann Professor of Computational Biomedical Engineering, Chemical and Biomolecular Engineering and Professor of Mathematics at Lehigh University. His research is directed toward numerical methods and associated software for ordinary, differential-algebraic and partialdifferential equations (ODE/DAE/PDEs), and the development of mathematical models based on ODE/DAE/PDEs. He is the author, coauthor or coeditor of 30+ books, and his ODE/DAE/PDE computer routines have been accessed by thousands of colleges and universities, corporations and government agencies

متن يادداشت

Covid-19 is primarily a respiratory disease which results in impaired oxygenation of blood. The O2-deficient blood then moves through the body, and for the study in this book, the focus is on the blood flowing to the brain. The dynamics of blood flow along the brain capillaries and tissue is modeled as systems of ordinary and partial differential equations (ODE/PDEs). The ODE/PDE methodology is presented through a series of examples, 1. A basic one PDE model for O2 concentration in the brain capillary blood. 2. A two PDE model for O2 concentration in the brain capillary blood and in the brain tissue, with O2 transport across the blood brain barrier (BBB). 3. The two model extended to three PDEs to include the brain functional neuron cell density. Cognitive impairment could result from reduced neuron cell density in time and space (in the brain) that follows from lowered O2 concentration (hypoxia). The computer-based implementation of the example models is presented through routines coded (programmed) in R, a quality, open-source scientific computing system that is readily available from the Internet. Formal mathematics is minimized, e.g., no theorems and proofs. Rather, the presentation is through detailed examples that the reader/researcher/analyst can execute on modest computers. The PDE analysis is based on the method of lines (MOL), an established general algorithm for PDEs, implemented with finite differences. The routines are available from a download link so that the example models can be executed without having to first study numerical methods and computer coding. The routines can then be applied to variations and extensions of the blood/brain hypoxia models, such as changes in the ODE/PDE parameters (constants) and form of the model equations

موضوع مستند نشده

COVID-19 (Disease) -- Mathematical models

موضوع مستند نشده

Neurologic manifestations of general diseases

شماره رده

نشانه اثر

مستند نام اشخاص تاييد نشده

Schiesser, W. E., author.

کشور

Iran

سازمان

University of Tehran. Library of College of Science

تاريخ عمليات

20221101

تاريخ و ساعت مذاکره و دسترسي

UT_SCI_BL_DB_1003601_0001.pdf

فرمت انتشار

e

نوع ماده

BL

کد کاربرگه

278840

پیشوند ISBD اعمال شده است

1

سطح دسترسي

a

تكميل شده

Y